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Imaging Studies

Magnetic resonance imaging (MRI) studies plays a central role in the diagnosis of PSC and holds significant promise as a method to predict disease outcomes. Consequently, the MRI PSC Working Group was established to provide a collaborative network that seeks to foster discovery and innovation regarding the application of MRI-based technologies in the diagnosis of PSC and detection of disease related complications.

Active areas of investigation include using magnetic resonance cholangiograms and elastography (MRE) to predict disease outcomes and describing the correlation between MRE and fibroscan.  Other areas of interest include the use of other MRI based technologies to diagnose both PSC and cholangiocarcinoma at an earlier stage.

Current projects  (June 2018)

  • Beatrice Madrazo, Miami, “MRI characteristics of macroregenerative nodules in PSC”
  • Vincenzo Cardinale & Domenico Alvaro, Rome, “Imaging of peribiliary glands and histo-morphology correlates in PSC and PSC/CCA”.
  • Andrea Tenca, Helsinki, “Is MRI a reliable method to detect dominant strictures and screen patients for dysplasia surveillance in PSC?”
  • Annika Bergquist, Stockholm, “MRI surveillance for CCA in PSC”
  • Sudhakar Venkatesh & John Eaton, Rochester: “Standardized MRI reporting system for patients with PSC”? and definition of the term “dominant stricture” using MRI
  • Roman Zenouzi and Christoph Schramm, Hamburg, “Early diagnosis of PSC using MRI”
  • Emina Halilbasic, Vienna: “MRI readouts for pharmacological studies in PSC” and Protocol for ongoing clinical studies
  • Henrike Lenzen & Kristina Ringe, Hannover: „MRI CCA localization – database“